Publicações

Link para as publicações de Karina Bortoluci : 

 

https://orcid.org/0000-0001-6780-5397

 

Publicações selecionadas:

 

- Matteucci, K, Pereira, GJS, Weinlich, R, Bortoluci, KR. Frontline Science: Autophagy is a cell autonomous effector mechanism mediated by NLRP3 to control infection. J Leukoc Biol. doi: 10.1002/JLB.HI1118-461R, 2019. 

 

- Pacheco AL, Vicentini G, Matteucci KC, Ribeiro RR, Weinlich R, Bortoluci KR. The impairment in the NLRP3-induced NO secretion renders astrocytes highly permissive to T. cruzi replication. J Leukoc Biol. doi: 10.1002/JLB.4AB1118-416RR, 2019. 

 

-Amarante-Mendes GP, Adjemian S, Branco LM, Zanetti LC, Weinlich R, Bortoluci KR. Front Immunol. 9:2379. doi: 10.3389/fimmu.2018.02379, 2018.

 

- Rodrigues-Junior DM, Biassi TP, Carlin V, Buri MV, Torrecilhas AC, Bortoluci KR, Vettore AL. OIP5 Expression Sensitize Glioblastoma Cells to Lomustine Treatment. J Mol Neurosci. 66(3):383-389. doi: 10.1007/s12031-018-1184-1, 2018.

 

 

- Buzzo de Lima C, Medina T, Branco L, Lage S, Ferreira LCS, Amarante-Mendes GP, Hottiger M, Carvalho DD, Bortoluci KR. Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage. Scientific Reports, 7:41686, 2017.

 

-Ersching J, Basso AS, Calich VL, Bortoluci KR*, Rodrigues MM*. A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells. PLoS Pathog. 2016; 12(6):e1005698. doi: 10.1371/journal.ppat.1005698. eCollection 2016.

*These authors share the sênior authorship

 

- Cassado A, D´império Lima MR, Bortoluci KR. Revisiting Mouse Peritoneal Macrophages: Heterogeneity, Development, and Function. Front Immunol. 6:225. doi: 10.3389/fimmu.2015.00225, 2015.

 

- Lage SL, Longo C, Branco LM, da Costa TB, Buzzo Cde L, Bortoluci KR. Emerging Concepts about NAIP/NLRC4 inflammasomes. Front Immunol. 5:309. doi: 10.3389/fimmu.2014.00309. eCollection 2014.

 

Amaral EP, Ribeiro SC, Lanes VR, Almeida FM, de Andrade MR, Bomfim CC, Salles EM, Bortoluci KR, Coutinho-Silva R, Hirata MH, Alvarez JM, Lasunskaia EB, D'Império-Lima MR. Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in agressive forms of tuberculosis. PLoS Pathog. 2014 Jul 3;10(7):e1004188. doi: 10.1371/journal.ppat.1004188. eCollection 2014 Jul.

 

- Lage L, Amarante-Mendes G, Bortoluci KR. Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin. Methods 61(2):110-116; 2013.

 

- Gomes, MTR, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR. Cunha LD, Zamboni DS, Oliveira SC. Critical Role of ASC Inflammasomes and Bacterial Type IV Secretion System in Caspase-1 Activation and Host Innate Resistance to Brucella abortus Infection. The Journal of Immunology, 190(7): 3629-3638, 2013.

 

- Vasconcelos JR, Bruna-Romero O, Araújo AF, Dominguez MR, de Alencar BCG, Machado AV, Gazzinelli RT, Bortoluci KR, Amarante-Mendes GP, Lopes MF and Rodrigues MM. Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: Reversal by adenoviral vaccine. Plos Pathogen. PLoS Pathogens, 8(5):e1002699, 2013.

 

- Lage SL, Buzzo CL, Amaral EP, Matteucci KC, Massis LM, Icimoto MY, Carmona AK, D'Império Lima MR, Rodrigues MM, Ferreira LC, Amarante-Mendes GP, Bortoluci KR. Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):E3321-30. doi: 10.1073/pnas.1305316110.

 

- Gonçalves VM, Matteucci KC, Buzzo CL, Miollo BH, Ferrante D, Torrecilhas AC, Rodrigues MM, Alvarez JM, Bortoluci KR. NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production. PLoS Negl Trop Dis. 2013 Oct 3;7(10):e2469. doi: 10.1371/journal.pntd.0002469.

 

- Lima-Junior DS, Costa DL, Carregaro V, Cunha LD, Silva AL, Mineo TW, Gutierrez FR, Bellio M, Bortoluci KR, Flavell RA, Bozza MT, Silva JS, Zamboni DS. Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania. Nat Med. 2013 Jul;19(7):909-15. doi: 10.1038/nm.3221.

 

- Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC Jr, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, BORTOLUCI KR, Bossis I, Bost F, Bourquin JP............ Matarrese, P Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4): 445-544, 2012.

 

-  Cassado A, de Albuquerque JA, Sardinha LR, Buzzo C de L, Faustino L, Nascimento R, Ghosn EE, Lima MR, Alvarez JM, Bortoluci KR.  Cellular renewal and improvement of local cell effector activity in peritoneal cavity in response to infectious stimuli. PLoS One. 6(7):e22141, 2011.

 

- Buzzo CL, Campopiano JC, Massis LM, Lage SL, Cassado AA, Leme-Souza R, Dias da Cunha L, Russo M, Zamboni DS, Amarante-Mendes GP, Bortoluci KR. A novel pathway for inducible nitric oxide synthase (iNOS) activation through inflammassomes. J. Biol. Chem. 285(42):32087-95, 2010

 

 Bortoluci KR, Medzhitov R. Control of infection by pyroptosis and atophagy: role of TLR and NLR. 2010. Cell Mol Life Sci.  67(10):1643-51, 2010.

 

- Ghosn EE, Cassado AA, Govoni GR, Fukuhara T, Yang Y, Monack DM, Bortoluci KR, Almeida SR, Herzenberg LA, Herzenberg LA. Two physically, funtionally, and developmentally distinct peritoneal macrophage subsets. Proc Natl Acad Sci U S A. 107(6):2568-73, 2010.